RHOFADE Cream reduced persistent facial redness due to rosacea in adults all day, through 12 hours on day 29.1

Before and Afters


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RHOFADE (oxymetazoline hydrochloride) CREAM, 1% is a prescription medicine used on the skin (topical) to treat facial redness due to rosacea that does not go away (persistent) in adults.


Before you use RHOFADE Cream, tell your healthcare provider about all of your medical conditions, including if you: have heart, blood vessel, or blood pressure problems, or narrow-angle glaucoma (call your healthcare provider or get medical help if these conditions worsen); have problems with blood circulation or have had a stroke; have Sjӧgren’s syndrome; have scleroderma; have Raynaud’s phenomenon; have thromboangiitis obliterans; have irritated skin or open sores on the face; are pregnant or plan to become pregnant; or are breastfeeding. It is not known if RHOFADE Cream will harm your unborn baby. It is not known if RHOFADE Cream passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you use RHOFADE Cream.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, skin products, vitamins, and herbal supplements. Using RHOFADE Cream with certain other medicines may affect each other and can cause serious side effects.

The most common side effects of RHOFADE Cream include application-site reactions of: skin reactions (dermatitis), worsening of rosacea pimples, itching, redness, and pain.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please click here for the RHOFADE Cream full Product Information.